| abstract |
The present invention provides antagonist antibodies or fragments thereof that bind to human OX40, methods for their preparation and methods for treating OX40-mediated disorders. A heavy chain CDR1 containing a specific amino acid sequence, and / or a heavy chain CDR2 containing a specific amino acid sequence, and / or a heavy chain CDR3 containing a specific amino acid sequence, and / or a light chain containing a specific amino acid sequence. An antagonist antibody or a fragment thereof that binds to human OX40, comprising a chain CDR1, and / or a light chain CDR2 containing a specific amino acid sequence, and / or a light chain CDR3 containing a specific amino acid sequence. [Selection figure] None |