| abstract |
The present invention provides a CK1 inhibitor and / or a circadian rhythm control agent having various activities using PHA as a lead compound and having a stronger activity. A compound represented by formula I, a salt thereof, or a solvate thereof. (R 1 is H or C 1-5 linear, branched or cyclic alkyl group, alkenyl group or alkynyl group, R 2 is H, halogen (F, Cl, Br or I), or C 1-4 alkyl group, ring A represents a 5- to 8-membered lactam ring; provided that R 1 and R 2 both exclude H. [Selection figure] None |