| abstract |
A novel conjugate of GDF15, a method for producing the same, and a method for using the same are provided. The fatty acid includes a biomolecule linked to a fatty acid via a linker, wherein the fatty acid is represented by the following formula A1, A2, or A3: [R 1 is CO 2 H or H, and R 2 , R 3 , and R 4 are independently of each other H, OH, CO 2 H, —CH═CH 2 , or —C≡CH. , Ak is a branched C 6 -C 30 alkylene, and n, m, and p are each independently an integer between 6 and 30], or an amide, ester thereof Or a pharmaceutically acceptable salt. [Selection figure] None |