Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_eec40d1e34ae619a1a28c526b18c6174 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1017 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H1-06 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-10 |
filingDate |
2019-08-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_843d09f5912a5afee2de6232afa422bc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b79360ef50b2b04bacd6b8cbe972cd81 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dbc615c21ca7bb4400e3ea5731760412 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cd61ae7b9259c96dffab67ed02e06955 |
publicationDate |
2019-12-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
JP-2019205472-A |
titleOfInvention |
Method for purifying messenger RNA |
abstract |
A method for purifying messenger RNA is provided. The present invention provides, inter alia, a method for purifying messenger RNA (mRNA), the method comprising (a) precipitating mRNA from an impure preparation, and (b) containing the precipitated mRNA. Subjecting the impure preparation to a purification step including membrane filtration in which the precipitated mRNA is captured by the membrane; and (c) eluting the captured precipitated mRNA from the membrane by resolubilization of the mRNA. And thereby obtaining a purified mRNA solution. In some embodiments, the purification step including membrane filtration suitable for the present invention is tangential flow filtration. [Selection figure] None |
priorityDate |
2014-04-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |