| abstract |
PROBLEM TO BE SOLVED: To provide a new and effective alternative diagnostic viewpoint for detection, monitoring and prediction of prostate cancer, particularly malignant hormone-sensitive prostate cancer. A marker for malignant hormone-sensitive prostate cancer of phosphodiesterase 4D7 (PDE4D7) whose expression is increased when the expression in malignant hormone-sensitive prostate cancer tissue is compared with that in normal tissue or benign prostate tumor tissue Use as. Compositions for diagnosing, detecting, monitoring or prognosing malignant hormone-sensitive prostate cancer, corresponding detection methods, methods enabling differentiation between benign and malignant hormone-sensitive prostate cancers, data collection methods and corresponding Immunological assay. A method of identifying individuals for eligibility for malignant hormone-sensitive prostate cancer and an immunological assay that stratifies individuals suffering from such prostate cancer. Pharmaceutical composition and use thereof for the treatment of malignant hormone sensitive prostate cancer. [Selection] Figure 4 |