Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a4afb11b9038232a630fc22a300b2717 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61J1-05 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-29 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-10 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61J1-05 |
filingDate |
2019-04-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b4c40e4b0dc7cb8585fcc230c8c95e85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f1dcea44172eee7b92421b656ed28aa0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9e138ba2ae7ea4dab820833f45eae3e8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_75aeb7796579b1232b25af52361cc48b |
publicationDate |
2019-11-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
JP-2019202127-A |
titleOfInvention |
Formulation with reduced N-formylpiperidine content and / or reduced collapse or shrinkage of lyophilized cake |
abstract |
[PROBLEMS] To suppress an increase in N-formylpiperidine over time in a preparation sealed with a rubber stopper and filled in a medical container. The production process of the preparation includes the following steps 1 and 2. Step 1) The preparation is sealed with a rubber plug having a dehydration rate of 33% / h or less according to the following definition; Definition) The rate of change in the amount of water contained in a rubber plug obtained after a sterilization treatment at 121 ° C. for 30 minutes as a water-containing treatment for a rubber plug, followed by a drying treatment for 1 hour. Water content of rubber plug after treatment / Water content of rubber plug after water treatment × 100 (% / hour); Step 2) The preparation is wound with an aluminum cap. [Selection figure] None |
priorityDate |
2018-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |