abstract |
The present invention provides viloxazine-related compounds such as viloxazine and various salts thereof, and novel intermediate reaction products and polymorphs thereof, and a method for producing them. A substantially pure API of viloxazine HCl is provided while avoiding undesirable impurities. The method further provides for the separation, identification and characterization of novel polymorphs of viloxazine. Further provided are methods for the synthesis and identification and characterization of viloxazine and novel intermediates of some important metabolites and precursors of viloxazine. [Selection] Figure 4 |