| abstract |
Disclosed is a pharmaceutical composition containing an active agent that provides long-term release of the active agent. An ionic complex comprising a cationic polypeptide and an anionic excipient selected from PEG-carboxylic acids, fatty acids having 10 or more carbon atoms, anionic phospholipids, and combinations thereof. A pharmaceutical composition comprising the ionic complex and a pharmaceutically acceptable carrier. Use of a pharmaceutical composition comprising said ionic complex for treating a subject suffering from a disease or disorder responsive to a cationic polypeptide of the ionic complex. [Selection figure] None |