Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_87a863132c68cf0f62015bbd5d05ab38 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-92 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-565 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-18 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-15 |
filingDate |
2019-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cd8601346f61aeddc0164979141f2af4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4db60c1e72fb83c23d1105d173ab12e6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_348c5e595411b2384c8f703b5cc9d3c9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_633939813e74ccaba8abd8f35bec8376 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4ed4452918b30b6844268211b5f85fdc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c3e60ae4f22057551a0da30d726109fb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_abae3697d2c472026d7bc98b32524732 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_22f591ed607f4d55d66f47861a0056eb |
publicationDate |
2019-10-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
JP-2019176866-A |
titleOfInvention |
Anti-PHF-tau antibody and use thereof |
abstract |
PROBLEM TO BE SOLVED: To prevent aggregation and / or prevent tauopathy progression of hyperphosphorylated form of microtubule-binding protein tau in fibrils called spiral fibrils (PHF) in Alzheimer's disease (AD) and related diseases. Anti-PHF-tau antibodies and methods of making and using the same. An isolated antibody that binds to PHF-tau comprising an antigen binding site of a heavy chain variable region having a specific sequence and an antigen binding site of a light chain variable region having a specific sequence. Producing an antibody that binds to PHF-tau, comprising a vector comprising an isolated polynucleotide encoding the antibody, a host cell comprising the vector, and culturing the host cell and recovering the antibody produced by the host cell how to. [Selection figure] None |
priorityDate |
2011-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |