abstract |
An antibody alternative derived from a carbohydrate binding module (CBM) family 32 protein, an affinity scaffold (non-immunoglobulin polypeptide framework). The affinity scaffold has the following formula: (a) CR1-V-CR2-W-CR3-Z-CR4, or (b) CR1-V-CR2-W-CR5-X-CR6-Y- CR7-Z-CR4, wherein V, W, X, Y, and Z each independently have a non-existing or specific amino acid, and the constant region CR1-CR7 has a specific amino acid sequence. And an affinity scaffold that specifically binds to the target molecule. [Selection figure] None |