| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5e5c121269689cbab9b3a4548b15caf3 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-61
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-519
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K33-24 |
| filingDate |
2018-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b442e05a7066720eaa8141daa93811f0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9d04d64feb844e757cb9a3b402db562b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_03e97c38ea9bd1eee60f5ff24ad0fe0c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9095a4344d45a0907a0f0bd06ed4a51f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b90bb56dde239eb48f048358f2ddf4e8 |
| publicationDate |
2019-09-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-2019156771-A |
| titleOfInvention |
Pemetrexed-hyaluronic acid conjugate |
| abstract |
An object of the present invention is to provide a compound effective for the treatment of disseminated tumors and a pharmaceutical composition containing the compound. A pemetrexed-hyaluronic acid conjugate is provided wherein pemetrexed is covalently linked to hyaluronic acid or a hyaluronic acid derivative directly or through a spacer. Also provided are pharmaceutical compositions comprising the pemetrexed-hyaluronic acid conjugate. The pharmaceutical composition may further contain a crosslinkable hyaluronic acid, and a pharmaceutical kit comprising a crosslinkable hyaluronic acid-containing pharmaceutical composition is also provided. [Selection figure] None |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115887687-A |
| priorityDate |
2018-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |