abstract |
Disclosed is a peptide, multimer, conjugate, analog, derivative, or mimetic thereof that inhibits the activity of VISTA. A peptide identical to a specific amino acid sequence (Ser-Ser-Ala-Cys-Asp-Trp-Ile-Lys-Arg-Ser-Cys-His), a multimer, a conjugate, an analog, a derivative thereof, or Isolated VISTA antagonists, including mimetics. In addition to treating or preventing cancer, bacterial infections, viral infections, parasitic infections, and fungal infections, the research use of antagonists is included. [Selection] Figure 1 |