| abstract |
A novel GLP-1 receptor modulator is provided. Provided are compounds that modulate the glucagon-like peptide 1 (GLP-1) receptor, methods for their synthesis, and methods for their therapeutic and / or prophylactic use. Such compounds may be used by themselves or with incretin peptides (eg, GLP-1 (7-36), GLP-1 (9-36) and oxyntomodulin) or peptide-based therapeutic agents (eg, Exenatide and liraglutide) can act as modulators or potentiators of the GLP-1 receptor and have the following general structure: where A, B, C, R 1 , R 2 , R 3 , R 4 , R 5 , n, p and q are as defined herein. [Selection figure] None |