abstract |
A method for directing maytansinoids targeting a selected cell population is provided. The method includes contacting a cell population or tissue suspected of containing a selected cell population with a cell binding agent maytansinoid complex, in which case one or more A maytansinoid is a method in which a cell-binding substance is covalently linked through a non-cleavable linker (for example, SMCC represented by the following formula), and the cell-binding substance binds to cells of a selected cell population. [Selection figure] None |