| abstract |
PROBLEM TO BE SOLVED: To provide a compound which is an inhibitor of Trk kinase and is useful in the treatment of pain, cancer, inflammation, neurodegenerative diseases and certain infectious diseases. In the following formula I, ring A, ring B, W, m, D, R 2 , R 2a , R 3 , R 3a and Z are defined as described in the specification of the present application Compounds, and pharmaceutically acceptable salts thereof, are inhibitors of Trk kinase and are useful in the treatment of pain, cancer, inflammation, neurodegenerative diseases, and certain infectious diseases is there. 【Selection chart】 None |