http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2019092645-A

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publicationDate 2019-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-2019092645-A
titleOfInvention Medical adhesive excellent in autolysis and adhesion, and powder spray device therefor
abstract An object of the present invention is to show excellent performance in adhesion strength due to gelation, hardenability, coatability, etc. with respect to a site where a large amount of body fluid exudes in surgery and other living tissues, and it has self-degradability and flexibility for living tissues. Provided are a medical adhesive that can be optionally adjusted, and a powder spray device therefor. A partially carboxylated poly is obtained by reacting a first reactant comprising powder of aldehyde-forming α-glucan with succinic anhydride or glutaric anhydride so that the percentage of remaining amino groups is 70 to 93%. Premixing with a second reactant consisting of L-lysine powder to form a mixed adhesive powder. Powder spray apparatus 10 comprising a funnel 1 for supplying mixed adhesive powder into an air flow pipe 4 for application and a vibration motor 2 for vibrating the same, and a bypass air flow pipe 8 for flowing compressed air during application and standby. The application is performed so that the amount of application once is 20 to 50 mg / cm 2 . [Selected figure] Figure 1
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