| abstract |
The present invention provides crystalline forms of anti-HCV compounds. SOLUTION: (1R, 5S, 8S, 9S, 10R, 22aR) -5-tert-butyl-N-[(1R, 2R) -2- (difluoromethyl) -1-{[(1-methylcyclopropyl] ) Sulfonyl] carbamoyl} cyclopropyl] -9-ethyl-18, 18-difluoro-14-methoxy-3, 6-dioxo-1, 1a, 3, 4, 5, 6, 9, 10, 18, 19, 20 , 21, 22, 22a-tetradecahydro-8H-7, 10-methanocyclopropa [18, 19] [1, 10, 3, 6] dioxadiazacyclononadeno [11, 12-b] quinoxaline Crystalline form of -8-carboxamide (formula (I) below). [Selected figure] Figure 1 |