abstract |
The present invention relates to a therapeutic agent that modulates signal transduction or function of interleukin-15 (IL-15) and an interaction between IL-15 and an IL-15 receptor, which is a therapeutic agent for regulating immune function. Providing a therapeutic that targets and modulates IL-15 induced signaling. An isolated cell recombinantly expressing human IL-15 and a soluble form of human interleukin-15 receptor alpha (IL-15Ra), and a method of producing IL-15 and IL-15Ra. [Selected figure] Fig. 1A-B |