| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fee0817238d9d83961482f55d2e80ce1 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-167
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B65B29-028
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5415
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5377
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-198
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-167
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-137
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-095
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7036
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61J1-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-08 |
| filingDate |
2019-01-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0da682bfb7bd456bdf4bc924b3395b57
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8e7b9798d7645c33584c9e19b9c8f3e5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b5df720a7c374966d435a648f5a6af9d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1bd743d78495067111ddefad2191c397
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0cb56cea0122d228593c91b09c94cbed
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_219e5674ad16a63edb904ac492c7a57c |
| publicationDate |
2019-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-2019081767-A |
| titleOfInvention |
Process for producing a stable ready-to-use infusion bag for oxidation sensitive formulations |
| abstract |
PROBLEM TO BE SOLVED: To provide a process for minimizing the formation of the most decomposition products during moist heat sterilization of a drug solution of an active pharmaceutical ingredient susceptible to oxidation. The pharmaceutical active ingredient susceptible to oxidation is mixed with an excipient and deoxygenated water to prepare a non-sterile drug solution. The non-sterile drug solution is filled into a moist heat sterilizable soft infusion bag. The soft infusion bag containing the non-sterile drug solution is subjected to final moist heat sterilization at a preset air overpressure of about 0.2 bar to about 1.2 bar to obtain a parenteral drug product. The process in which the highest degradation products in parenteral drug products are less than 0.5% by weight of the labeled amount of the active pharmaceutical ingredient susceptible to oxidation in parenteral drug products. 【Selection chart】 None |
| priorityDate |
2013-04-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |