| abstract |
The present invention provides an improved system, apparatus, and method for care and assessment of perfusion status useful for effective preservation of the heart ex vivo. A method for producing / generating lactate in the absence of oxygen and using unique characteristics of cardiomyocytes which metabolise / use lactate for energy production when perfused with oxygen sufficiently 2.) Arterial blood lines and veins of the organ care system cardiac perfusion device to assess the total perfusion status of the isolated heart, 2) the metabolic status of the extracted heart, and 3) the total vascular patency of the extracted donor heart. Systems, devices, and methods for measuring and comparing lactate values in blood lines and showing proper perfusion and oxygenation close to physiological conditions for cardiomyocytes. 【Selection chart】 None |