Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5f6c0ffe769a8911a5367e4492832ec4 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2800-413 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2800-412 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2800-31 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2800-84 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-044 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-37 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-375 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-676 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-553 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-604 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-678 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61Q19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-92 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-0291 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-198 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61Q19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-67 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-225 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-661 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-375 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-37 |
filingDate |
2017-10-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1165858bcca400b52795cafa7cf9db58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_47295b2da955cd226c22b29aa6242535 |
publicationDate |
2019-05-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
JP-2019069912-A |
titleOfInvention |
Non-aqueous skin external composition and method for producing the same |
abstract |
The present invention provides a non-aqueous skin external composition comprising a strongly hydrophilic amphiphilic solid active ingredient solubilized in an oil phase. A non-aqueous skin external composition comprising a strongly hydrophilic amphiphilic solid active ingredient-surfactant complex dissolved or dispersed in an oil phase as particles having a particle diameter of 2 nm to 200 nm. A strongly hydrophilic amphiphilic solid active ingredient is added to the aqueous phase to obtain an aqueous phase mixture, a surfactant is added to the oil phase to obtain an oil phase mixture, and the resulting aqueous phase mixture and the oil phase mixture are The mixture is mixed to obtain a water-in-oil emulsion, and the obtained water-in-oil emulsion is lyophilized to obtain a strongly hydrophilic amphiphilic solid active ingredient-surfactant complex, and the obtained strongly hydrophilic amphiphilic Hydrophobic active ingredient-surfactant complex is dissolved or dispersed in oil solution to dissolve or disperse strongly hydrophilic amphiphilic solid active ingredient-surfactant complex as particles of 2 nm to 200 nm in particle diameter in oil phase The manufacturing method of the non-aqueous skin external composition which let it solubilize a strongly hydrophilic amphiphilic solid active ingredient in an oil phase. 【Selection chart】 None |
priorityDate |
2017-10-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |