| abstract |
PROBLEM TO BE SOLVED: To provide an antibody directed to an E. coli MDR strain with improved specificity for use in the prevention or treatment of an E. coli infection caused by an LPO O25b-containing strain. The present invention provides an isolated antibody that specifically binds multi-drug resistant (MDR) O25b antigen of E. coli strains, its use in medicine and diagnostics, methods of preparing that antibody. Furthermore, it comprises isolated nucleotide sequences, plasmids and host cells used for the preparation of antibodies; and additionally isolated epitopes which are recognized by specific antibodies. [Selected figure] Figure 6 |