| abstract |
The present invention provides a kit for promoting non-cellular tooth tissue regeneration, which enables effective tooth tissue regeneration even when autologous or allogeneic stem cells or stem cell-derived components are not transplanted. SOLUTION: The non-cellular root canal filling comprising a pretreatment agent containing serine protease, a regeneration promoting compound containing at least one of a CCR3 antagonist, a CCL11 neutralizing antibody and an ALK5 inhibitor, and an extracellular matrix And a material. Preferably used for middle and old aged individuals. [Selected figure] Figure 1 |