| abstract |
PROBLEM TO BE SOLVED: To provide a novel salt and polymorphic crystalline form of omecamutibumecarvir useful as a therapeutic agent for heart failure. The dihydrochloride salt of omecamtibu mecarbyl having the following structure: The salt exhibits an X-ray powder diffraction pattern including peaks at about 6.6, 14.9, 20.1, 21.4 and 26.8 ± 0.2 ° 2θ by CuKα irradiation, and a differential scanning calorimetry It is preferred that the crystalline form has an endothermic transition at about 230 ° C. to about 240 ° C., as measured by measurement. 【Selection chart】 None |