| abstract |
An inhibitor of ERK and methods of use are provided. The present invention provides chemical entities or compounds capable of modulating specific protein kinases such as ERK (MAPK), and pharmaceutical compositions thereof. Methods of using such compounds or compositions, and compositions for treating one or more of these kinases, particularly for therapeutic use such as treating disorders such as cancer. Methods used to adjust are also provided. In another aspect, the present invention provides a method of inhibiting the activity of a protein kinase present in a cell. 【Selection chart】 None |