| abstract |
In view of the potential shortcomings of current methods in drug release by coated devices, a drug delivery platform is provided that provides delivery with a defined release profile of a biologically active agent. An article comprising a coated surface, wherein the coated surface has the formula (I) Bio 1 -Link 1- (Bio 2 -R 1 ) m (I) (where Bio 1 is Formed from a biologically active agent; m is 1 to 5; each Bio 2 is absent or formed independently from a biologically active agent, where Each Bio 2 contains a covalent bond to Link 1 , if present; R 1 is present only in the absence of Bio 2 ; Link 1 is an oligomeric, having a molecular weight of 60-2000 Daltons, A compound having a structure of organic, organic silicon or organic sulfone). [Selection] Figure 6 |