http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2019030242-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_afcfc7af43784847a2171ad49795c3c3 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-15 |
filingDate | 2017-08-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4c5dc980b0c0fbc7aff180cb49859c0d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_705888992913a78ff79ede4492ca5ecf |
publicationDate | 2019-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2019030242-A |
titleOfInvention | Method for screening hepatitis B virus (HBV) growth inhibitor |
abstract | Disclosed is a drug having a therapeutic effect by a mechanism different from that of a conventional therapeutic agent for hepatitis B. The present invention provides an assay method for screening candidate substances that inhibit the growth of hepatitis B virus (HBV). The method of the present invention comprises the steps of incubating a substrate comprising the r sequence of HBV relaxed circular DNA (rcDNA) with flap endonuclease 1 (FEN1) and detecting cleavage of the r sequence, In the presence or absence of the candidate substance. [Selection figure] None |
priorityDate | 2017-08-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 297.