| abstract |
PROBLEM TO BE SOLVED: To provide a screening method for an anticancer agent that can be used for prevention or treatment of cancer by targeting a ruthereal mutant specifically found in cancer patients as a tumor marker and a target for cancer treatment. (A) a step of separating a mutant luteal or normal rutheal from a bodily fluid already drained from a patient or a normal person, and (b) an anticancer agent or a cancer preventive candidate for the separated rutheal variant. Treating the substance, and (c) a candidate substance that reduces the size, changes the morphology, or increases the motility of the mutant as compared to the control group before the candidate substance treatment, as an anticancer agent, Or selecting a candidate substance that suppresses the increase in the size of the ruterial, minimizes morphological change, or maintains motility as compared with the control group before the candidate substance treatment as a cancer preventive substance. Anticancer drug or cancer preventive drug screening method. [Selection] Figure 36 |