| abstract |
PROBLEM TO BE SOLVED: To provide an agent that can be used to increase sRAGE and / or increase the level of adiponectin and / or lower the level of thrombomodulin, and to treat indications such as kidney disease. Do. A method of transplantation, replacement or tissue, cells or one or more organs (e.g., kidney, heart valve (e.g. replacement or repair of aortic heart valve) comprising administering to a patient an effective amount of MetAP2 inhibitor) Methods are provided in potential transplant or replacement patients to improve the outcome of surgery to implant a joint, eg, a knee or hip replacement. 【Selection chart】 None |