Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4021f8d8a53258a5a3615b4139dd1eee |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P19-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-80 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4703 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P19-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-195 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4703 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0602 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-22 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7088 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-46 |
filingDate |
2018-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_776d22894be2ac1a339540d4976db98b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cd895f4ef7fd83068c4b19128cb1df5b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b029c7dba8c8b1a799310887f533da7f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f23203e8fa0fae8a0a4f1cd9bfacc2fb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4b38250d57c99c600e8bb3f1723c587a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_524a7a8fff27c6abc46ce7854706c0f1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0b0848c5637775e209ddf19760f0b883 |
publicationDate |
2019-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
JP-2019010119-A |
titleOfInvention |
Method for producing compact TALE-nuclease and use thereof |
abstract |
Provided is a method for producing a compact transcriptional activator-like effector nuclease (TALEN) capable of efficiently targeting and processing double-stranded DNA. (A) selecting one DNA target sequence of interest on one strand of double-stranded DNA; (b) (i) an iteration having DNA binding specificity for said DNA target sequence of interest One core TALE scaffold comprising a variable dipeptide region (RVD), (ii) a catalytic domain comprising a meganuclease variant with cleavage activity on said double-stranded DNA, (iii) optionally providing a compact TALEN monomer; (c) in vitro such that the double stranded DNA is processed with the unique monomer and the double stranded at a position several base pairs away 3 'and / or 5' from the single stranded target sequence. A method of targeting and processing double-stranded DNA in vitro, comprising contacting. [Selection] Figure 1 |
priorityDate |
2011-04-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |