http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2019001811-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_58d9f89504cb81aa43ed41e076d50b31 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-13 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4184 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4184 |
filingDate | 2018-09-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1ac958f4b374962ce6c8afe4dfc1e720 |
publicationDate | 2019-01-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2019001811-A |
titleOfInvention | 2-((R) -2-methylpyrrolidin-2-yl) -1H-benzimidazole-4-carboxamide crystal form 1 |
abstract | 2-((R) -2-methylpyrrolidin-2-yl) -1H-, which is a poly (ADP-ribose) polymerase (PARP) inhibitor and is also referred to as ABT-888, which is easy to produce and prepare. Provided are benzimidazole-4-carboxamide crystal form 1, a production method thereof, a composition containing the same and a production method using the same, and a method for treating a patient having a disease using the same. When measured at about −100 ° C. in a square crystal system and a P43212 space group with radiation at 0.7107 個 々, the individual lattice parameter values a, b and c are 8.218 Å ± 0.002 Å, 8 2-((R) -2-methylpyrrolidin-2-yl) -1H-benzimidazole having 218Å ± 0.002Å and 36.06Å ± 0.01Å and α, β and γ values of 90 ° 4-Carboxamide crystal form 1. [Selection figure] None |
priorityDate | 2007-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 618.