| abstract |
The present invention relates to an indoline-2-one derivative represented by the general formula (I) (wherein the substituents are defined in claim 1). This compound has positive symptoms (psychiatric) and negative symptoms of schizophrenia, drug abuse, alcohol and drug addiction, obsessive compulsive disorder, cognitive impairment, bipolar disorder, mood disorder, major depression, treatment-resistant depression, Anxiety disorder, Alzheimer's disease, autism, Parkinson's disease, chronic pain, borderline personality disorder, neurodegenerative disease, sleep disorder, chronic fatigue syndrome, stiffness, inflammatory disease, asthma, Huntington's disease, ADHD, muscle atrophic lateral cord CNS associated with sclerosis, effects on arthritis, autoimmune diseases, viral and fungal infections, cardiovascular diseases, ophthalmic diseases and inflammatory retinal diseases, and neurodevelopmental disorders with balance sensory disorders, epilepsy, and comorbid epilepsy It can be used in the treatment of disease. |