abstract |
Inhibitors of wild type RET and its resistant mutants, pharmaceutical compositions comprising such compounds, and methods of using such compounds and compositions. In another aspect, the present invention provides a method of inhibiting RET activity in a cell or in a patient. In some embodiments, the method comprises contacting the cell with a compound of structural formula (I) or a pharmaceutically acceptable salt or composition thereof, or the compound or salt or composition. Administering to said patient. [Selection figure] None |