| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-723
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-7028
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-582
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-60
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5047
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5026
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5011 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57434 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N15-00 |
| filingDate |
2016-09-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate |
2018-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-2018535432-A |
| titleOfInvention |
Androgen receptor variant 7 as a biomarker for treatment selection in patients with metastatic castration-resistant prostate cancer (mCRPC) |
| abstract |
The present invention is a method of identifying patients with metastatic castration resistant prostate cancer (mCRPC) with improved response to taxane therapy compared to androgen receptor (AR) targeted therapy, comprising: Performing direct analysis, including immunofluorescent staining and morphological characterization of nucleated cells in a collected blood sample to generate circulating tumor cell (CTC) data, wherein the analysis comprises Detecting the presence of androgen receptor variant 7 (AR-V7), and (c) evaluating this CTC data and improving response to taxane therapy compared to ARS-directed therapy A method comprising the step of identifying mCRPC patients with [Selection] Figure 1A |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2020529023-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11789023-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-7040816-B2 |
| priorityDate |
2015-09-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |