| abstract |
The present invention relates to particles comprising a drug and a ligand, and methods for making and using the same. In particular, the present invention provides for covalent capture of large amounts of drug onto polymer carriers for controlled release, such as (nano) particles, microspheres, and other types of polymer devices. The polymer carrier or device can be attached with a ligand to achieve targeting and / or (non) invasive monitoring to a particular tissue. |