http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2018533968-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2740-15043 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2740-16043 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-622 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-03 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-02 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-7051 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-70578 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2803 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-49 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-867 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 |
| filingDate | 2016-11-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2018-11-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2018533968-A |
| titleOfInvention | Optimized lentiviral transfer vector and its use |
| abstract | The invention features lentiviral transfer vectors containing heterologous nucleic acids to be introduced into cells. The lentiviral transfer vector has the following characteristics: (a) containing a cytomegalovirus (CMV) promoter, (b) a partial gag protein containing a mutated INS1 inhibitory sequence that reduces the restriction of nuclear export of RNA (C) containing no polynucleotide encoding (c) gag INS2, INS3, and INS4 inhibitory sequences, (d) not containing an SV40 replication origin and / or an f1 replication origin, e) containing cPPT sequences containing splice sites, (f) containing EF1 alpha promoter with intact splice donor and acceptor sites, and (g) type B with mutations in the start codon of the ORF of the X protein It can be characterized by including hepatitis PRE . |
| priorityDate | 2015-11-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 839.