| abstract |
Disclosed herein are compounds comprising dicarba-closo-dodecaborane. The compound can be, for example, an estrogen receptor beta (ERβ) agonist. In some instances, the compound may be a selective ERβ agonist. Also provided herein is administering to a subject a therapeutically effective amount of one or more of the compounds or compositions described herein, or a pharmaceutically acceptable salt thereof, Methods of treating, preventing or ameliorating cancer in a subject, methods of inhibiting tumor growth in a subject, methods of treating inflammatory disease, methods of treating neurodegenerative disease in a subject, psychotropic activity in a subject Methods of treating sexual disorders, or a combination thereof. |