| abstract |
The present disclosure features novel lipids and compositions containing the same. The nanoparticle composition includes novel lipids and additional lipids such as phospholipids, structured lipids, and PEG lipids. A nanoparticle composition further comprising a therapeutic and / or prophylactic agent, such as RNA, for example, for the therapeutic and / or prophylactic agent to a mammalian cell or organ to modulate polypeptide, protein, or gene expression. Useful for delivery. |