| abstract |
The present disclosure relates to sexually transmitted disease ribonucleic acid vaccines and combination vaccines, and methods of using the vaccines and compositions comprising the vaccines. The present invention is, for example, a sexually transmitted disease (STD) vaccine, comprising at least one RNA polynucleotide having an open reading frame encoding at least one STD antigen polypeptide, formulated with cationic lipid nanoparticles. Also provided is a sexually transmitted disease (STD) vaccine. In one embodiment, the antigenic polypeptide is selected from human papillomavirus (HPV), herpes simplex virus (HSV), and Chlamydia trachomatis antigen polypeptide. [Selection] Figure 4 |