| abstract |
The present invention can transduce T cells such as CD8 + T cells, CD4 + T cells, CD3 + T cells, γδ T cells or natural killer (NK) T cells transduced with CXCR6 for tumor targeted therapy, such T cells. The present invention relates to a nucleic acid sequence, a vector, a transduced T cell having the nucleic acid sequence or vector of the invention, a method and a kit comprising the nucleic acid sequence or vector of the invention. The invention also relates to the use of the transduced T cells in a method for treating a disease characterized by CXCL16 overexpression, as well as a trait expressing CXCR6 for use in a method of treating a disease characterized by CXCL16 overexpression. Pharmaceutical compositions / medicaments comprising the introduced T cells are provided. [Selection] Figure 1 |