http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2018530588-A
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-545 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-572 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-20034 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-20022 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-21 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-0208 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-195 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-245 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-39 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-0011 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-39 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
filingDate | 2016-10-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2018-10-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2018530588-A |
titleOfInvention | Recombinant Listeria vaccine strain and methods of use in cancer immunotherapy |
abstract | The present invention involves the treatment, prevention, and eliciting an immune response thereto of a human papillomavirus-related tumor or cancer comprising the step of administering to a subject a recombinant Listeria strain that expresses a construct comprising at least one human papillomavirus antigen. Provide a way to do it. The present invention is an immunogenic composition comprising, for example, a recombinant Listeria strain comprising a recombinant nucleic acid, wherein the nucleic acids are tandemly linked in a tandem fashion to provide four heterologous HPV antigens Or a heterologous HPV antigen or functional fragment thereof comprising a first open reading frame encoding a recombinant polypeptide comprising a functional fragment thereof and operably linked to the N-terminus of the heterologous antigen at the N-terminal end. Wherein the recombinant nucleic acid is fused to an N-terminal fragment of the LLO protein, wherein the recombinant nucleic acid further comprises a second open reading frame encoding a metabolic enzyme. [Selection] Figure 1 |
priorityDate | 2015-10-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1925.