| abstract |
Methods, uses, pharmaceutical regimens, pharmaceutical compositions, and kits comprising modulators of TLR8 and pharmaceutically acceptable salts thereof useful for the treatment of HIV infection are provided. In one aspect, a method of treating human HIV infection is provided, the method comprising: a) reducing HIV levels detected in human blood or plasma from a first level to a second level. Administering a sufficient pharmaceutically effective amount of a combined antiretroviral therapy regimen to a human in need of treatment, wherein the second level is the first level of human blood or plasma HIV concentration And b) administering to the human a pharmaceutically effective amount of a TLR8-modulating compound, or a pharmaceutically acceptable salt thereof. . |