http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2018527012-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6806 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6839 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6876 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6844 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6816 |
| filingDate | 2016-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2018-09-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2018527012-A |
| titleOfInvention | Methods and compositions for genomic target enrichment and selective DNA sequencing |
| abstract | It has been established that one or more large double stranded DNA fragments (each having a size of 2,000-40,000 bases) can be captured and isolated from genomic DNA fragments using sequence specific PNA hybridization probes. Yes. Compositions and methods for enriching multiple long DNA sequences selected from any eukaryotic genome are provided. Capture uses multiple PNA molecules with a gamma modified chiral backbone, including a mixture of neutral chemical groups and positive chemical groups such as diethylene glycol, gamma-L-lysine, gamma-L-thialysine, etc. To be implemented. Two or more PNA probes with covalently linked haptens, preferably biotin, are included for capture, isolation of multiple enriched targets, including DNA methylation sequencing, and subsequent sequencing analysis. Target the DNA domain. |
| priorityDate | 2015-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 872.