| abstract |
The formulation for eye treatment includes a photosensitizer and a transmission enhancing composition. The permeability enhancing composition includes one or more permeability enhancing agents. The transmission enhancing composition has a hydrophilic and lipophilic balance and increases the permeability of the eye area for the light enhancing agent. The hydrophilic and lipophilic balance can be characterized by a hydrophilic-lipophilic balance (HLB) value. For example, the ocular region can comprise a corneal epithelium, the light enhancer can comprise riboflavin, and the permeability enhancing composition has a corresponding HLB value between about 12.6 and about 14.6. Can do. |