abstract |
An imidazo [4,5-c] ring compound having a guanidine substituent at the 1-position (especially imidazo [4,5-c] quinoline, 6,7,8,9-tetrahydroimidazo [4,5-c] quinoline, Imidazo [4,5-c] naphthyridine and 6,7,8,9-tetrahydroimidazo [4,5-c] naphthyridine compound), pharmaceutical compositions containing the above compounds, and methods for producing the above compounds are disclosed The Also disclosed are methods of using the above compounds as immune response modifiers to induce cytokine biosynthesis in animals and in the treatment of diseases such as viral and neoplastic diseases. |