| abstract |
The present invention relates to novel geminal substituted aminobenzisoxazole compounds suitable as α7-nAChR agonists or partial agonists, and pharmaceutical compositions of the foregoing, methods for preparing these compounds and compositions, and cognitive function. It relates to the use of these compounds and compositions in methods of maintenance, treatment and / or amelioration. In particular, a method of administering a compound or composition to a patient in need thereof who may benefit from it, such as a patient having a desire to enhance cognitive impairment and / or cognitive function. |