abstract |
The present invention relates to conditions associated with eye damage, skin disorders, damaging effects from erosive agents, as well as autoimmune diseases, inflammatory diseases through the use of primary amines that scavenge toxic aldehydes such as MDA and HNE. Provides for the treatment, prevention, and / or reduction of the risk of diseases, disorders, or conditions in which aldehyde toxicity is associated with pathogenesis, including neurological and cardiovascular diseases. The compounds and compositions thereof of the present invention are useful for treating, preventing and / or reducing the risk of diseases, disorders or conditions in which aldehyde toxicity is associated with pathogenesis. |