abstract |
The present invention reduces one or more adverse effects of eye diseases such as abnormal intraocular pressure, retinal vascular disease, retinal ganglion cell death, or combinations thereof to reduce vision impairment and to reduce vision impairment. A method for treating is provided. The method comprises a plurality of particles of uniform size distribution, a therapeutic amount of a therapeutic agent selected from a voltage-gated calcium channel antagonist, an endothelin receptor antagonist, or a combination thereof; and an optional additional therapeutic agent A flowable particulate composition comprising a particulate formulation having a uniform particle size distribution, each particle comprising a matrix, and a pharmaceutically acceptable carrier. . [Selection] Figure 1 |