abstract |
The present invention relates to the amino acid modifications 7Lys, 30Trp and 31Leu, and PYY compounds with 22Ile and / or 28Tyr in addition thereto, and derivatives thereof. The compounds of the present invention are selective Y2 receptor agonists. The invention also relates to pharmaceutical compositions comprising such PYY compounds and a pharmaceutically acceptable excipient, and to the medical use of PYY compounds. |