abstract |
The present invention provides therapeutic and diagnostic methods and compositions for cancer, such as bladder cancer. The present invention relates to a method of treating bladder cancer, a method of determining whether a patient suffering from bladder cancer is likely to respond to treatment comprising a PD-L1 axis binding antagonist, suffering from bladder cancer Methods for predicting responsiveness of a patient to a treatment comprising a PD-L1 axis binding antagonist, and expression levels of biomarkers of the invention (eg, PD-L1 expression levels in tumor infiltrating immune cells in a tumor sample obtained from a patient) ) And / or based on the determination of the tumor sample subtype, a method of selecting a therapy for a patient suffering from bladder cancer is provided. [Selection figure] None |